Long live the Nucleobase!

Multiple medical and biological sensors and targeted drug delivery are based in the functionalization of nanoparticles (NPs) with biomolecules. The role of the NPs is to enhance the optical response of the target surroundings. But this enhancement comes with a huge risk: this same radiation can severily damage DNA or RNA producing mutations.

Johannes Feist (UAM) together with groups from the University of Modena and the University of Munich, have studied in which conditions these NPs can act as a protection for the biomolecules (in this case Uracil) while being effective in their sensing/therapeutic function. And importantly, the results proposed in their research can be easily implemented with the current nanophotonic technology.

This paper, published in the Journal of Physical Chemistry Letters, has been recognized with the cover we designed together with the supervision of Dr. Feist.

Posted in Cover, Picture and tagged , , .