Anti-metastatic treatment for breast cancer

Nanosized drug delivery systems based strategies are slowly changing our view of medical treatment. They can be applied to a wide variety of diseases and Dr. María J. Vicent (Polymer Therapeutics Lab) and Dr. Marcelo Calderón (POLYMAT) are designing new approaches expand their usage and improve their efficiency.


In their last work, they deal with triple negative breast cancer and its associated metastasis, for which we lack effective treatments. In their recent paper in Journal of Controlled Release, they propose “injectable poly-amino acid-based nanogels as a versatile hydrophilic drug delivery platform for the treatment of triple negative breast cancer lung metastasis”. These nanogels deliver the chemotherapeutic agents in more restricted, specific areas increasing their efficiency thus reducing their aggressiveness.

We designed this representation of the drug delivery process under the supervision of  María J. Vicent and Marcelo Calderón. Their work has been featured at the cover of JCR.

Drug Transport in 3D Tumor Model

We’ve already work for Prof. Calderon and his group in the past. They seem the kind of people that work directly to enlarge our life expectancy. Their main research is focused in the delivery of drugs through physiological barriers. They’ve made an important advance recently by studying how nanogels can help in the transport of drugs inside tumor tissue.

Their research, reported in Theranostics, has been awarded with the cover of the journal.